Histiocytic cytophagic panniculitis: Report of a case and long-course treatment effects


DEMİRİZ M., Pay S., Caliskaner Z., Baykal Y., Celasun B., Finci R.

Turkish Journal of Dermatopathology, cilt.6, sa.1-2, ss.30-33, 1997 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 1-2
  • Basım Tarihi: 1997
  • Dergi Adı: Turkish Journal of Dermatopathology
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.30-33
  • Anahtar Kelimeler: hemaphagocytosis, histiocytic cytophagic panniculitis
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

We describe a young man with a rapid course of systemic illness characterized by erythematous nodular, even solitary subcutaneous lesions, remittent fever, anemia, thrombocytopenia, leukopenia, splenomegaly, hepatomegaly, weight loss and tachycardia. Skin biopsy showed the histopathological findings of lobular histiocytic panniculitis with 'bean-bag' cells which were characteristic of histiocytic cytophagic panniculitis (HCP). No infectious agent could be detected and, there was no histological evidence of neoplasia. Immunohistochemical stains confirmed the presence T lymphocytes in addition to histiocytes and neutrophils within the adipose tissue. Findings of the case even tachycardia responded to treatment with long-course corticosteroid (CS) and chloroquine. The pertinent literature on HCP has been reviewed and some exceptional findings of the case were discussed.