Letter to the Editor: Comment on Gümüş et al.’s “Toluene-Related Toxic Optic Neuropathy: A Case Report”
Neuro-Ophthalmology, cilt.50, sa.4, ss.397-398, 2026 (ESCI, Scopus)
- Yayın Türü: Makale / Kısa Makale
- Cilt numarası: 50 Sayı: 4
- Basım Tarihi: 2026
- Doi Numarası: 10.1080/01658107.2026.2675330
- Dergi Adı: Neuro-Ophthalmology
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO)
- Sayfa Sayıları: ss.397-398
- Anahtar Kelimeler: Toxic optic neuropathy, toluene, methanol, anion gap, metabolic acidosis
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
We highlight key diagnostic gaps in a reported case of toluene-related toxic optic neuropathy, including the absence of anion gap calculation, lack of explicit methanol exclusion, and incomplete temporal characterization of visual symptoms. A comprehensive toxicological workup–including serum methanol levels, osmolar gap, and metabolic profiling–is essential to distinguish toluene from methanol or mixed solvent toxicity in cases of acute bilateral visual loss.