The Effect of Preemptive Ketamine on Analgesia and Analgesic Consuption after Tonsillectomy Preemptif Uygulanan Ketamin Tonsillektomi Sonrasi Analjezi ve Analjezik Tüketimine Etkisi
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, cilt.31, sa.5, ss.247-252, 2003 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 5
- Basım Tarihi: 2003
- Dergi Adı: Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.247-252
- Anahtar Kelimeler: Analgesic consumption, And postoperative analgesia, Ketamine, Preemptive analgesia, Verbal pain scale
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
We aimed to observe the effects of ketamine in subanaesthetic doses when used in different stages of surgery. The ethical committee approved the study. Forty-five patients aged between 5-15 scheduled for elective tonsillectomy/adenotonsillectomy were divided into equal three groups. The preemptive group (Group P) received ketamine 0.5 mg kg-1 IV in 2 mL saline at tonsillectomy position, followed by a continuous IV infusion of ketamine 6 μg kg-1 min-1, and during haemostasis 2 mL saline was administered. In the ketamine group (Group K) 2 mL saline were given at tonsillectomy position, and saline infusion (10 mL h-1) continued until haemostasis, when 0.8 mg kg-1 ketamine was given in 2 mL saline. In the control group, 2 mL saline was given at tonsillectomy position and saline infusion (10 mL h-1) continued until haemostasis. At the haemostasis 2 mL saline was administered. When VPS is greater than 3; tramadol 1 mg kg-1 IV in the first 6 hours, and after 6 hours paracetamol 40 mg kg-1 orally was given. Cardiores-piratory system data, extubation time, the post anaesthesia care unit (PACU) receiving time, discharging time from PACU, tramadol and paracetamol requirement, total dose of paracetamol, and complications were recorded. Recovery from anaesthesia and discharging parameters were similar between the groups. Total dose of paracetamol in the preemptive group was lower than the other groups. In the preemptive group VPS scores were lower than the other two groups at the early post-operative period, and only than the control group at the 6th hour (p<0.05). Severe secretion was observed in the group ketamin. We concluded that ketamine decreases postoperative analgesic requirement and has analgesic effect when used preemptively in tonsillectomy/adenotonsillectomy.