Genodermatosis: A retrospective study Genodermatozlar: Retrospektif bir çalişma
Turkderm Deri Hastaliklari ve Frengi Arsivi, cilt.40, sa.4, ss.133-135, 2006 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 40 Sayı: 4
- Basım Tarihi: 2006
- Dergi Adı: Turkderm Deri Hastaliklari ve Frengi Arsivi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.133-135
- Anahtar Kelimeler: Genodermatosis, Retrospective study
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background and Design: Genodermatosis, have a significant place in the skin diseases, involving more than 200 diseases. There is no significant study in frequency and abundance of genodermatosis in our country. In this study we tried to emphasize the frequency and abundance of genodermatosis with high number of cases. Materials and Methods: We detected 1303 records of cases, who were diagnosed to have a genodermatosis among 400.000 cases who admitted to our outpatient service or hospitalized in our department between 1981-2005. Results: Among 400.000 cases, these 1303 cases have an occurance rate of 0.325 %. If evaluated on the basis of individual diseases, localised palmoplantar keratoderma 232 (17.8 %), ichthyosis vulgaris 201 (15.4 %), epidermolysis bullosa 175 (13.4 %), neurofibromatosis 97 (7.4 %), ichthyosis lamellaris 91 (6.9 %), Darier's disease 66 (5.1 %), Klippel-Trenaunay syndrome 46 (3.5 %), xeroderma pigmentosum 44 (3.4 %), oculocutaneous albinism 35 (2.6 %) and ectodermal dysplasia 29 (2.2 %) are the ten most frequent ones. In our cases if the first 5 of these genodermatosis evaluated geographically, highest number of the cases were from Southeastern Anatolia, with Inner Anatolia and Blacksea regions following it. In Marmara and Aegean regions, the number of genodermatosis is lower. High prevalence of in Southeast and Inner Anatolian regions suggets that there are more kin-marriages in these regions. Conclusion: Today, genetic counselling to families holds an important place in the prevention of this kind of diseases. So determining the rate of this diseases and regions where they occur, will be helpful in preventive medicine.