Epicardial Adipose Tissue Thickness and Related Factors in Patients with Ankylosing Spondylitis Ankilozan Spondilit Hastalarında Epikardial Adipoz Doku Kalınlığı ve İlişkili Faktörler
Turk Osteoporoz Dergisi, cilt.30, sa.3, ss.171-177, 2024 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 3
- Basım Tarihi: 2024
- Doi Numarası: 10.4274/tod.galenos.2024.34966
- Dergi Adı: Turk Osteoporoz Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.171-177
- Anahtar Kelimeler: Ankylosing spondylitis, atherosclerosis, epicardial adipose tissue thickness, body mass index, sacroiliitis
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: This study aimed to investigate epicardial adipose tissue thickness (EATT) and related factors in patients with ankylosing spondylitis (AS) and to compare the results with those of healthy controls. Materials and Methods: This cross-sectional study included 30 patients diagnosed with AS based on the modified New York criteria. The control group consisted of 31 healthy volunteers. Demographic characteristics were recorded, and EATT was measured by transthoracic echocardiography. The Bath AS Disease Activity Index (BASDAI), Bath AS Functional Index (BASFI), Bath AS Metrology Index (BASMI), AS Disease Activity Score (ASDAS), AS Quality of Life (ASQoL), and International Physical Activity Questionnaire Short Form were used. Functional capacity was assessed using the six-minute walk test (6-MWT). Results: The mean age was 41.67±7.56, and 21 (70%) participants were male in the AS group. The mean disease duration was 10.0 (standard deviation ±7.2) years in the AS group. The mean EATT values were 4.40±1.65 mm and 2.85±1.12 mm in the AS and control groups, respectively (p<0.001). A notable negative correlation was observed between EATT and erythrocyte sedimentation rate (ESR) (p<0.05). Significant positive correlations were also observed between EATT and body mass index (BMI), BASFI, and BASMI. Additionally, EATT was linearly associated with the severity of sacroiliitis (r=0.400, p=0.028). There were no significant correlations between EATT and disease duration, C-reactive protein levels, blood lipid levels, ASDAS, ASQoL, IPAQ, and 6-MWT (p>0.05). Conclusion: EATT values were higher in patients with AS than in those without AS. The factors related to EATT were BMI, ESR, BASFI, BASMI, and the severity of sacroiliitis.