Bone marrow suppression and klebsiella pneumonia septicemia due to ticlopidine and successful treatment with filgrastim; a case report


Korkmaz M., ÇEKİN A. H.

International Journal of Cardiology, cilt.66, sa.3, ss.317-318, 1998 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Kısa Makale
  • Cilt numarası: 66 Sayı: 3
  • Basım Tarihi: 1998
  • Doi Numarası: 10.1016/s0167-5273(98)00219-8
  • Dergi Adı: International Journal of Cardiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.317-318
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

In this report we describe an elderly lady, who after 27 days of ticlopidine treatment developed severe pancytopenia and gram (-) septicemia. No clinical response was obtained with an eight days course of empirical broad spectrum antibiotics, after which granulocyte colony stimulating factor (G-CSF, filgrastim) added to her regimen. In a period of seven days her neutrophil count was normal and she had recovered from septicemia. Twelve weeks after discharge she is fine and her blood parameters are all normal.