Serum endocan levels, carotid intima-media thickness and microalbuminuria in patients with newly diagnosed hypertension
Clinical and Experimental Hypertension, cilt.41, sa.8, ss.787-794, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 41 Sayı: 8
- Basım Tarihi: 2019
- Doi Numarası: 10.1080/10641963.2019.1652632
- Dergi Adı: Clinical and Experimental Hypertension
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.787-794
- Anahtar Kelimeler: Endocan, hypertension, microalbuminuria
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Endocan is a particular protein of endothelial cells. The purpose of this study was to determine the relationship of serum endocan levels with carotid intima-media thickness (cIMT), inflammation, and microalbuminuria in patients with newly-diagnosed hypertension. Materials-Methods: This prospective study included 61 patients with newly-diagnosed hypertension (HT) and 30 controls. Endocan, microalbuminuria and cIMT measurements were taken from all patients. Results: The serum endocan levels, the mean cIMT and microalbuminuria levels of patients with HT were significantly higher than those of the control group (p <.0001, p =.015 and p <.001, respectively). Conclusion: We found that endocan levels were increased in our study. This increase in endocan levels shows a relation with cIMT and microalbuminuria, which are associated with endothelial dysfunction.