Uveitis as a Confounding Factor in Retinal Nerve Fiber Layer Analysis Using Optical Coherence Tomography
Ocular Immunology and Inflammation, cilt.30, sa.2, ss.386-391, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 2
- Basım Tarihi: 2022
- Doi Numarası: 10.1080/09273948.2020.1811353
- Dergi Adı: Ocular Immunology and Inflammation
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.386-391
- Anahtar Kelimeler: Uveitis, glaucoma, retinal nerve fiber layer, optical coherence tomography
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose: To investigate the retinal nerve fiber layer thickness (RNFLT) in uveitic eyes and search for the associations with uveitis activity, etiology and location. Methods: The files of 76 patients with uveitis and 76 controls were scanned. Associations of RNFLT were analyzed using generalized linear models. Results: The RNFLT was significantly higher in patients with uveitis (p <.001). Active uveitis patients had a thicker RNFL than the controls and the patients with quiescent uveitis (p <.001). Anterior uveitis was associated with thinner RNFL in global and inferotemporal quadrant (p =.011 and 0.013, respectively). Thickening of RNFL was associated with posterior uveitis and Behçet’s disease in all quadrants (p <.001) and idiopathic uveitis in the superonasal and nasal quadrants (p =.001). Conclusion: Active uveitis, as well as posterior uveitis and Behcet’s disease-associated uveitis, is a major confounding factor in RNFL analysis and therefore detection of glaucoma.