Rosmarinus officinalis L.
Novel Drug Targets with Traditional Herbal Medicines: Scientific and Clinical Evidence, Springer International Publishing Ag, ss.525-541, 2022
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2022
- Doi Numarası: 10.1007/978-3-031-07753-1_34
- Yayınevi: Springer International Publishing Ag
- Sayfa Sayıları: ss.525-541
- Anahtar Kelimeler: Biological activity, Phenolic compounds, Rosemary, Rosmarinic acid, Toxicity
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Rosmarinus officinalis L. (Rosemary) is a medicinal and aromatic herb belonging to the Lamiaceae family. The geographical distribution of the plant covers especially the Mediterranean Region and regions with a Mediterranean climate. In addition, it has been cultured in many countries around the world so far. The aerial components of the plant, particularly the leaves, are rich in both volatile and nonvolatile phytochemicals: terpenes, flavonoids, phenolic compounds, alcohols, and esters. Phenolic compounds such as carnosol, carnosic acid, and rosmarinic acid in its content have been associated with the plant’s anticancer, anti-inflammatory, antihyperglycemic, antithrombotic, and antioxidant activities. The antimicrobial and antioxidant bioactivities of its essential oil have been utilized and accepted as a safe conservator in the food industry. While the bioactivity of the plant has been proven by in vivo and in vitro experiments, the results of clinical studies support the existence of these bioactivities. The potential of rosemary to be transformed into herbal medicine is considerable. In this chapter, we present an overview of the distribution, ethnobotany, bioactive and nutritional composition and available extraction techniques, scientific evidences, clinical and toxicological studies, available commercial formulations, and challenges and future recommendations as potential drug candidate of rosemary.